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CBD Infused Extra Virgin Olive Oil

 

What is CBD?

Cannabis is a plant of the Cannabaceae family and contains more than eighty biologically active

chemical compounds. The most commonly known compounds are delta-9-tetrahydrocannabinol

(THC) and cannabidiol (CBD). THC is the component that produces the “high” associated with

marijuana use. Much interest has been seen around CBD and its potential related to health

benefits. Marijuana is different from CBD. CBD is a single compound in the cannabis plant, and

marijuana is a type of cannabis plant or plant material that contains many naturally occurring

compounds, including CBD and THC.

 

Why do we add CBD to olive oil in tinctures?

We add CBD to olive oil because we believe it to be a better vehicle for the cbd as they share

similar anti inflammatory properties The Endocannabinoid System plays a big role in keeping

your internal processes stable. But there’s still a lot of unknowns. As experts develop a better

understanding of the ECS, it could eventually hold the key to treating several conditions.

 

The endocannabinoid system (ECS)

A complex cell-signaling system identified in the early 1990s by researchers exploring THC, a

well-known cannabinoid. Cannabinoids are compounds found in cannabis. Experts are still

trying to fully understand the ECS. But so far, we know it plays role in regulating a range of

functions and processes, including:

  1. sleep
  2. mood
  3. appetite
  4. memory
  5. reproduction and fertility

The ECS exists and is active in your body even if you don’t use cannabis.

Read on to learn more about the ECS including how it works and interacts with cannabis.

 

How does it work?

The ECS involves three core components: endocannabinoids, receptors, and enzymes.

 

  1. Endocannabinoids

Endocannabinoids, also called endogenous cannabinoids, are molecules made by your body.

They’re similar to cannabinoids, but they’re produced by your body.

Experts have identified two key endocannabinoids so far:

  1. anandamide (AEA)
  2. 2-arachidonoylglycerol (2-AG)

These help keep internal functions running smoothly. Your body produces them as needed,

making it difficult to know what typical levels are for each.

  1. Endocannabinoid receptors

These receptors are found throughout your body. Endocannabinoids bind to them in order to

signal that the ECS needs to take action. There are two main endocannabinoid receptors:

  1. CB1 receptors, which are mostly found in the central nervous system
  2. CB2 receptors, which are mostly found in your peripheral nervous system, especially

immune cells

Endocannabinoids can bind to either receptor. The effects that result depend on where the

receptor is located and which endocannabinoid it binds to. For example, endocannabinoids

might target CB1 receptors in a spinal nerve to relieve pain. Others might bind to a CB2

receptor in your immune cells to signal that your body’s experiencing inflammation, a common

sign of autoimmune disorders.

3 Enzymes

Enzymes are responsible for breaking down endocannabinoids once they’ve carried out their

function. There are two main enzymes responsible for this:

  1. fatty acid amide hydrolase, which breaks down AEA
  2. monoacylglycerol acid lipase, which typically breaks down 2-AG

 

What are its functions?

The ECS is complicated, and experts haven’t yet determined exactly how it works or all of its

potential functions. Research (NIH 2) has linked the ECS to the following processes:

  • appetite and digestion
  • metabolism
  • chronic pain
  • inflammation and other immune system responses
  • mood
  • learning and memory
  • motor control
  • sleep
  • cardiovascular system function
  • muscle formation
  • bone remodeling and growth
  • liver function
  • reproductive system function
  • stress
  • skin and nerve function

These functions all contribute to homeostasis, which refers to stability of your internal

environment. For example, if an outside force, such as pain from an injury or a fever, throws off

your body’s homeostasis, your ECS kicks in to help your body return to its ideal operation.

Today, experts believe that maintaining homeostasis is the primary role of the ECS.

 

How does THC interact with the ECS?

Tetrahydrocannabinol (THC) is one of the main cannabinoids found in cannabis. It’s the

compound that gets you “high.” Once in your body, THC interacts with your ECS by binding to

receptors, just like endocannabinoids. It’s powerful partly because it can bind to both CB1 and

CB2 receptors. This allows it to have a range of effects on your body and mind, some more

desirable than others. For example, THC may help to reduce pain and stimulate your appetite.

But it can also cause paranoia and anxiety in some cases. Experts are currently looking into

ways to produce synthetic THC cannabinoids that interact with the ECS in only beneficial ways.

 

How does CBD interact with the ECS?

The other major cannabinoid found in cannabis is cannabidiol (CBD). Unlike THC, CBD doesn’t

make you “high” and typically doesn’t cause any negative effects. Experts aren’t completely

sure how CBD interacts with the ECS. But they do know that it doesn’t bind to CB1 or CB2

receptors the way THC does. Instead, many believe it works by preventing endocannabinoids

from being broken down. This allows them to have more of an effect on your body. Others

believe that CBD binds to a receptor that hasn’t been discovered yet. While the details of how it

works are still under debate, research suggests that CBD can help with pain, nausea, and other

symptoms associated with multiple conditions.

 

What about endocannabinoid deficiency?

Some experts believe in a theory known as clinical endocannabinoid deficiency (CECD). This

theory suggests that low endocannabinoid levels in your body or ECS dysfunction can

contribute to the development of certain conditions. A 2016 article (NIH ) reviewing over 10

years of research on the subject suggests the theory could explain why some people develop

migraine, fibromyalgia, and irritable bowel syndrome.

None of these conditions have a clear underlying cause. They’re also often resistant to

treatment and sometimes occur alongside each other.

If CECD does play any kind of role in these conditions, targeting the ECS or endocannabinoid

production could be the missing key to treatment, but more research is needed.

Sources:

NIH1 - Clinical Endocannabinoid Deficiency Reconsidered: Current Research Supports the

Theory in Migraine, Fibromyalgia, Irritable Bowel, and Other Treatment-Resistant Syndromes

NIH 2 - Cannabinoid Receptors and the Endocannabinoid System: Signaling and Function in

the Central Nervous System